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  • Title: [The possibilities of isoptin treatment of pulmonary hypertension in patients with chronic obstructive bronchitis].
    Author: Kakhnovskiĭ IM, Sivkov SI, Markova ZS, Ivanova IL, Sivkov AS.
    Journal: Klin Med (Mosk); 1997; 75(12):48-52. PubMed ID: 9503814.
    Abstract:
    The study included 30 patients with COB coursing from 5 to 15 years, free of chronic cor pulmonale symptoms. All the patients had moderate obstructive impairment of pulmonary ventilation with hemodynamic disorders and defects in myocardial contractility indicating the presence of transitory pulmonary hypertension (PH). Patients of the control group received conventional therapy. It was combined with isoptin-retard (240 mg/day) in the study group. The treatment produced a positive effect in all the patients, but those of the study group exhibited more pronounced decrease in pulmonary artery pressure, achieved better hemodynamics and myocardial contractility. Isoptin-retard in daily dose 240 mg is recommended in COB patients to prevent onset of chronic cor pulmonale.
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