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  • Title: 2-Mercapto-N-(azolyl)benzenesulphonamides. IV. Syntheses of some 4-chloro-2-mercapto-5-methyl-N-(benzimidazol-2-yl)benzenesulph onamide derivatives with potential anticancer and anti-HIV activities.
    Author: Pomarnacka E, Brzozowski Z.
    Journal: Acta Pol Pharm; 1997; 54(3):215-21. PubMed ID: 9511447.
    Abstract:
    Syntheses of 4-chloro-2-mercapto-5-methyl-N-(5-R1-6-R2-benzimidazol-2-yl) benzenesulphonamides [II-V], their disulfides [IIa-IVa] and S,N-substituted derivatives [VI-IX] were described. The probable mechanism for the reactions was suggested. The moderate anticancer activity was observed in vitro for compounds [II-IV].
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