These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Co-localization of polar replication fork barriers and rRNA transcription terminators in mouse rDNA.
    Author: López-estraño C, Schvartzman JB, Krimer DB, Hernández P.
    Journal: J Mol Biol; 1998 Mar 27; 277(2):249-56. PubMed ID: 9514756.
    Abstract:
    We investigated the replication of the region where transcription terminates in mouse rDNA. It contains a replication fork barrier (RFB) that behaves in a polar manner, arresting only replication forks moving in the direction opposite to transcription. This RFB consists of several closely spaced fork arrest sites that co-localize with the transcription terminator elements, known as Sal boxes. Sal boxes are the target for mTTF-I (murine transcription termination factor I). These results suggest that both termination of rRNA transcription and replication fork arrest may share cis-acting as well as trans-acting factors.
    [Abstract] [Full Text] [Related] [New Search]