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Title: Antigenic characteristic of the lipopolysaccharides of Coxiella burnetii isolates. Author: To H, Hotta A, Yamaguchi T, Fukushi H, Hirai K. Journal: J Vet Med Sci; 1998 Feb; 60(2):267-70. PubMed ID: 9524957. Abstract: Lipopolysaccharides (LPSs) of 8 isolates of Coxiella burnetii from a variety of clinical and geographical sources could be divided into four groups based on molecular heterogeneity in silver-stained sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) profiles in the region of the 10 to 17 kDa. The lipopolysaccharide of group 1 was identified on isolates from acute Q fever patient, milk and tick. The three remaining groups were primarily found on isolates from human cases of chronic Q fever. These LPSs shared many antigenic epitopes, as determined by immunoblotting with mouse anti-C. burnetii antisera.[Abstract] [Full Text] [Related] [New Search]