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  • Title: Intradural retroclival chordoma without bone involvement: no tumor regrowth 5 years after operation. Case report.
    Author: Nishigaya K, Kaneko M, Ohashi Y, Nukui H.
    Journal: J Neurosurg; 1998 Apr; 88(4):764-8. PubMed ID: 9525726.
    Abstract:
    Chordomas are most commonly located in the extradural region. A 56-year-old man presented with a large chondroid chordoma located totally within the intradural retroclival region. The tumor was resected via the petrosal approach. Five years after subtotal removal, the residual tumor showed no sign of regrowth despite the fact that radiation therapy had not been used. The patient was free of symptoms except for moderate, conductive hearing loss in his right ear. The position of the intradural tumor could be preoperatively diagnosed by neuroimaging and, thus, the petrosal approach was selected. Primary intradural extraosseous chordomas are very rare and difficult to differentiate from ecchordoses physaliphorae on the basis of histological and radiological features; however, MIB-1 staining may be useful.
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