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  • Title: Effect of isoproterenol on urinary function in goats.
    Author: Vandeputte-Van Messom G, Peeters G.
    Journal: Arch Int Pharmacodyn Ther; 1976 Apr; 220(2):346-7. PubMed ID: 952590.
    Abstract:
    Intraventricular administration of small doses (6.3-19-58 ng/kg/min) of isoproterenol (ISO) in non-hydrated goats produced a diuretic response, a decrease in urinary Na+, K+ and Cl- excretion and an increase in free water clearance. The diuretic response of ISO could be blocked by propranolol, but not by phentolamine. The data suggest that hypothalamic beta-adrenoceptors are involved in the inhibition of ADH release.
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