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  • Title: Complement component profiles in urticaria, dermatitis herpetiformis, and alopecia areata.
    Author: Berrens L, Jankowski E, Jankowski-Berntsen I.
    Journal: Br J Dermatol; 1976 Aug; 95(2):145-52. PubMed ID: 952750.
    Abstract:
    Insignificant variation was noted in the mean levels of the complement components CIQ, C4, C2, C3, C5 and C3PA between various groups of sera from patients with urticaria, angio-oedema, dermatitis herpetiformis, alopecia areata, or hay fever. No deficiencies were found. Elevated C9 levels in chronic urticaria and angio-oedema reflected its nature as an acute phase protein. The assessment of C components in single or sequential serum samples revealed only marginal variations. Similar results were recorded for plasminogen the immunoglobulins, G, A and M. Some evidence is provided for the primary involvement of the kallikrein-kinin system in urticaria.
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