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  • Title: [An operative case of primitive neuroectodermal tumor in the posterior mediastinum].
    Author: Inaba H, Ohta S, Nishimura T, Takamochi K, Ishida I, Etoh T, Honda A, Nakajima N, Muro H, Nagashima Y.
    Journal: Kyobu Geka; 1998 Mar; 51(3):250-3. PubMed ID: 9528236.
    Abstract:
    A primitive neuroectodermal tumor (PNET) is very rare and the prognosis of this tumor is poor. A 32-year-old woman complaining of dysphagia and back pain was admitted to our hospital for the posterior mediastinal tumor. The tumor originated from the muscle layer of esophagus and en bloc resection of the tumor combined with the affected part of esophagus was performed. Histopathological diagnosis of the resected tumor was PNET. She received adjuvant chemotherapy. Eight months after the surgery, recurrent tumors in the right mediastinum and the retrooperitoneal space was resected completely. But after the second surgery, dissemination occurred recurrently. These recurrent tumors revealed high sensitivity for radio-therapy. However, she died of rapid recurrence 22 months after the first surgery. In Japan, our case is the second case of PNET in the posterior mediastinum and the first case of PNET arising from the muscle layer of esophagus.
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