These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Detrimental effect of hypothermia during acute normovolaemic haemodilution in anaesthetized cats.
    Author: Talwar A, Fahim M.
    Journal: Int J Biometeorol; 1998 Feb; 41(3):113-9. PubMed ID: 9531854.
    Abstract:
    Haemodynamic responses to hypothermia were studied at normal haematocrit and following the induction of acute normovolaemic haemodilution. Experiments were performed on 20 cats anaesthetized with a mixture of chloralose and urethane in two groups. In one group (n = 10) the effects of hypothermia on various haemodynamic variables were studied at normal haematocrit (41.0 +/- 1.7%) and in the second group of cats (n = 10) the effects of hypothermia on various haemodynamic variables were studied after the induction of acute normovolaemic haemodilution (14.0 +/- 1.0%). The haemodynamic variables left ventricular pressure, left ventricular contractility, arterial blood pressure, heart rate and right atrial pressure were recorded on a polygraph. Cardiac output was measured using a cardiac output computer. In both groups hypothermia was induced by surface cooling with the help of ice. Cardiovascular variables were recorded at each 1 degree C fall in body temperature. Hypothermia produced a significant (P < 0.05) drop in heart rate, cardiac output, arterial blood pressure and left ventricular contractility in both groups. However, the percentage decrease in these variables in response to hypothermia was significantly (P < 0.05) higher in cats with low haematocrit than in those with normal haematocrit. The severity of hypothermia--induced cardiovascular effects is evident from the drastic decrease in heart rate, cardiac output, arterial blood pressure and myocardial contractility in cats with low haematocrit, indicating a higher risk of circulatory failure under anaemic conditions at low temperatures.
    [Abstract] [Full Text] [Related] [New Search]