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  • Title: [The neuropathies of IgM monoclonal gammopathies].
    Author: Humbel RL, Schmit P, Gilson G.
    Journal: Bull Soc Sci Med Grand Duche Luxemb; 1997; 134(2):11-5. PubMed ID: 9534268.
    Abstract:
    A peripheral polyneuropathy is often associated with an IgM monoclonal gammapathy. The monoclonal protein often binds to carbohydrate epitopes on glycoproteins and/or glycolipids of the human peripheral nerve. The clinical syndrome is related to the antigen-specificity of the IgM protein. Detection of anti-myelin antibodies and further characterization of their immunogenic specificity provide an important aid in the differential diagnosis of late-onset chronic polyneuropathies.
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