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Pubmed for Handhelds

PUBMED FOR HANDHELDS

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  • Title: Prevalence of natural rubber latex allergy (type I and type IV) in laboratory workers in The Netherlands.
    Author: de Groot H, de Jong NW, Duijster E, Gerth van Wijk R, Vermeulen A, van Toorenenbergen AW, Geursen L, van Joost T.
    Journal: Contact Dermatitis; 1998 Mar; 38(3):159-63. PubMed ID: 9536409.
    Abstract:
    The objective of the study was to study the prevalence of Type IV and Type I allergy to natural rubber latex (NRL) in a population at risk in the Netherlands. Laboratory workers regularly using gloves were invited to complete a questionnaire and to be tested. We performed patch tests with standard contact allergens, rubber additives, glove powder and pieces of 4 gloves; prick tests with inhalant allergens, glove extracts, glove powder and fruit extracts; and RASTs. Glove-related hand dermatitis was reported in 36.9% of the individuals interviewed. A positive patch test result for rubber additives was seen in only 6.6%. Glove-related urticaria, rhinoconjunctivitis and/or asthma were reported in 24.6% of all cases. Confirmation of an IgE-mediated reaction was achieved in 8.3% by prick test with glove extracts and 5.0% by RAST. No reaction to glove powder was noticed in patch testing or in prick testing. A high prevalence rate of glove-related symptoms and NRL Type I allergy was found in laboratory workers exposed to rubber gloves. Surprisingly, there was no co-existence of Type I and Type IV allergy in this population.
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