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  • Title: Antigenic structure of foot and mouth disease virus type A22 (Indian isolates).
    Author: Tulasiram P, Suryanarayana V.
    Journal: Indian J Exp Biol; 1998 Jan; 36(1):70-5. PubMed ID: 9536655.
    Abstract:
    Variations in foot and mouth disease virus are due to amino acid substitutions in the VP1, which is a major immunogen. Analysis of this hypervariable region is essential to know the antigenic structure of the serotype and is necessary to select a suitable vaccine strain. FMDV type A22 is one of the four prevailing virus types for which the vaccine is used regularly. To understand the antigenic structure of this type, carboxy- terminal region of VP1 from two field isolates and vaccine virus were sequenced and analysed. The results indicate that, Indian A22 has distinct antigenic structure.
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