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  • Title: Amide derivatives with H1-antihistaminic effect.
    Author: Saturnino C, Saturnino P, De Martino G, Lancelot JC, Perrine D, Boureau R, Robba M.
    Journal: Pharm Acta Helv; 1998 Jan; 72(5):279-83. PubMed ID: 9540460.
    Abstract:
    The synthesis and the structure-activity correlation of a series of N-aminoalkylacetamides as H1-antihistaminic agents have been carried out. The compounds were tested in vitro by measurement of the inhibition of histamine-induced contractions on isolated guinea pig ileum; the results are expressed as pA2.
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