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  • Title: Survival after massive arsenic poisoning self-treated by high fluid intake.
    Author: Kamijo Y, Soma K, Asari Y, Ohwada T.
    Journal: J Toxicol Clin Toxicol; 1998; 36(1-2):27-9. PubMed ID: 9541037.
    Abstract:
    A 23-year-old male pharmacist ingested 1040 mg arsenic trioxide (788 mg trivalent arsenic, 13 mg/kg). After 7 asymptomatic hours, frequent vomiting and diarrhea occurred. Fearing death from shock, he drank 5 L of water over 5 hours. When he was brought to our hospital with chief complaint of constricted vision about 20 hours after ingestion, the major abdominal symptoms had already subsided. Despite a lethal plasma arsenic on admission, all toxic symptoms including hepatic dysfunction, erythematous dermal eruption, and peripheral neuropathy improved during his hospital stay with no treatment except for dimercaptopropanol.
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