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  • Title: Changes in hepatic fatty acid degradation and blood lipid and ketone body content during development of the rat.
    Author: Foster PC, Bailey E.
    Journal: Enzyme; 1976; 21(5):397-407. PubMed ID: 954713.
    Abstract:
    The following have been measured during the development of the laboratory rat: the rate of oxidation of palmitoylcarnitine, decanoylcarnitine, and 14C-palmitate by liver mitochondria; the concentrations of ketone bodies in the blood; the plasma concentrations of non-esterified fatty acids, glycerol, and triglyceride. In each case, a rise after birth and a fall at weaning were observed. These changes can be correlated with the dietary changes which occur at these times. However, during the suckling period, when a constant high fat content diet is consumed, further marked changes in the parameters measured were observed which cannot be related to nutritional factors.
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