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  • Title: The effects of various agents in vitro on homocarnosine-carnosine synthetase from rat brain.
    Author: Ng RH, Marshall FD.
    Journal: Experientia; 1976; 32(7):839-41. PubMed ID: 954961.
    Abstract:
    The present paper reports the first evidence that homocarnosine-carnosine synthetase from rat brain requires free sulfhydryl groups for activity. The activity of the synthetase can be stabilized by dithioerythritol and inhibited strongly by Cu2+, Cd2+, Hg2+, Zn2+, and to a lesser extent by Ca2+, Ni2+, Li, chlorpromazine, alpha-methyl DOPA and norepinephrine at the concentrations tested.
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