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  • Title: [Complications of polychemotherapy for renal tuberculosis].
    Author: Kul'chavenia EV, Kuznetsov PV.
    Journal: Probl Tuberk; 1998; (1):28-30. PubMed ID: 9553430.
    Abstract:
    The paper analyzes the incidence of adverse reactions caused by tuberculostatics used in the treatment of renal tuberculosis by follow-ups of 117 patients. Current polychemotherapy for renal tuberculosis has been found to be complicated by drug intolerance in 40.1% of cases. Intermittent intravenous injection of tuberculostatics causes side effects in 36.8% of patients while conventional treatment does in 59.1%. Pyrazinamide, streptomycin, and ethambutol are most toxic to patients with renal tuberculosis. There is a higher likelihood of drug intolerance in females with bilateral nephrotuberculosis complicated by chronic renal failure.
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