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  • Title: Unilateral peripapillary myelinated retinal nerve fibers associated with strabismus, amblyopia, and myopia.
    Author: Lee MS, Gonzalez C.
    Journal: Am J Ophthalmol; 1998 Apr; 125(4):554-6. PubMed ID: 9559744.
    Abstract:
    PURPOSE: To describe the association of unilateral peripapillary myelinated retinal nerve fibers with myopia, strabismus, and amblyopia and to propose a possible pathologic mechanism. METHODS: Four patients who have the findings associated with unilateral peripapillary myelinated nerve fibers are described and reviewed. RESULT: All patients had poor visual outcomes despite treatment with full cycloplegic refraction and appropriate patching. CONCLUSIONS: Although the origin of this association is unknown, we believe that peripapillary myelinated nerve fibers in a unilateral myopic eye may be secondary to an imbalance between the process of myelination and the formation of the lamina cribrosa. Good results have been reported with amblyopic therapy; however, it is our experience that these patients are somewhat refractory to amblyopia therapy.
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