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  • Title: [Neovascularization of pre-formed tissue flaps in relation to arteriovenous blood flow of the implanted vascular pedicle. Experimental study in the rabbit].
    Author: Klöppel M, Nguyen TH, Graf P, Laubenbacher C, Höhnke C, Schwaiger M, Biemer E.
    Journal: Langenbecks Arch Chir Suppl Kongressbd; 1997; 114():1379-80. PubMed ID: 9574434.
    Abstract:
    In 45 Chinchilla-Bastard rabbits, a skeletonised arterio-venous pedicle was implanted on the subsurface of a 15 x 8 cm abdominal skinflap to create a neovascularised axial prefabricated flap. In order to evaluate the potency of neovascularisation in relation to the blood flow of the pedicle, we compared minimal blood flow by distal ligation (model 1) with maximal blood flow by distal microvascular arteriovenous shunt anastomoses (model 2) of the implanted vascular pedicle. The results show that 8 and 12 days after pedicle implantation, tissue flap perfusion in model 2 is significantly earlier and better in comparison to model 1.
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