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  • Title: [The pharmacological correction of factors limiting human work capacity].
    Author: Seĭfulla RD.
    Journal: Eksp Klin Farmakol; 1998; 61(1):3-12. PubMed ID: 9575403.
    Abstract:
    The problem of pharmacological correction of working capacity and rehabilitation after exhausting physical exertion is discussed from the standpoint of current advances and detection of factors limiting man's working capacity. The removal of factors interfering with the development of optimal possibilities of man through the effect of medicinal drugs is considered. The article discusses the energy sources providing for the performance of physical work differing in power and duration in accordance with the specificity of a type of sports as a most convenient model for studying adaptation to physical exertion. Factors limiting the working capacity of athletes are classified on the basis of current advances in biochemistry and physiology. All pharmacological agents influencing human working capacity are classified according to the potency zones determining the supply of energy. Pharmacological monitoring of man's capacity for work is in fact disclosure of factors limiting it and their pharmacological correction. This allows planning of the means for excluding the use of dope drugs in sports medicine and scientifically substantiated use of drugs in heavy branches of industry, for promoting climato-zone adaptation, and in extreme conditions. It is shown that the use of strongly active drugs is not necessary because a large reserve is available of drugs of plant and animal origin possessing much lesser side effects.
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