These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Quinidine syncope. A report of successful treatment with bretylium tosylate.
    Author: VanderArk CR, Reynolds EW, Kahn DR, Tullett G.
    Journal: J Thorac Cardiovasc Surg; 1976 Sep; 72(3):464-7. PubMed ID: 957762.
    Abstract:
    Quinidine syncope is an unpredictable side effect of quinidine administrateion which has a mortality rate of 11.5 per cent when managed with conventional drugs and direct-current countershock. In 2 patients with quindine syncope, the arrhythmias were effectively controlled within 30 minutes following the slow infusion of 150 mg. of bretylium tosylate. This control is contrasted with 2 cases managed in the conventional manner. Bretylium tosylate is a quaternary amine with unique antifibrillatory properties and appears to have a significant role in the management of these arrhylmias.
    [Abstract] [Full Text] [Related] [New Search]