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  • Title: Treatment of T prolymphocytic leukemia with allogeneic bone marrow transplantation.
    Author: Collins RH, Piñeiro LA, Agura ED, Fay JW.
    Journal: Bone Marrow Transplant; 1998 Mar; 21(6):627-8. PubMed ID: 9580345.
    Abstract:
    T prolymphocytic leukemia (T-PLL) is an unusual disease characterized by high white cell counts, older age at presentation, splenomegaly and a very aggressive clinical course. We describe a 47-year-old male with refractory T-PLL who was treated with high-dose chemoradiotherapy and allogeneic bone marrow transplantation (BMT) from an HLA-matched sibling. The transplant was complicated by both acute and chronic graft-versus-host disease (GVHD). The patient achieved complete remission and remains in remission 3 years after the transplant.
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