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  • Title: Unexpected late graft failure 9 months after HLA-identical bone marrow transplant (BMT) for chronic myeloid leukemia (CML): treatment with a second BMT.
    Author: Gil-Fernández JJ, Arranz R, Cámara R, Alegre A, Figuera A, Fernández-Rañada JM.
    Journal: Haematologica; 1998 Mar; 83(3):285-7. PubMed ID: 9580418.
    Abstract:
    We describe a patient with CML in 1st chronic phase (CP) who experienced a graft failure 9 months after an HLA genotypically identical sibling BMT. Drug toxicity, viral infections, chronic graft-versus-host-disease (GVHD) or leukemic relapse were excluded. Chimerism study showed 85% of donor marrow cells. She underwent a second BMT, reengrafted but died of grade IV acute GVHD.
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