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  • Title: [The role of the epiphysis in forming a conditioned reaction to time in rats].
    Author: Arushanian EB, Vodolazhskaia MG.
    Journal: Zh Vyssh Nerv Deiat Im I P Pavlova; 1998; 48(1):54-9. PubMed ID: 9583164.
    Abstract:
    Pinealectomy impeded formation of time-conditioned reflex in the mode of fixed intervals. This was accompanied by a shortening of reaction latency and runs as well as by an increase in the number of intertrial responses. On the contrary, melatonin injection (0.1 mg/kg) facilitated conditioning by restricting the locomotion. It is suggested that pineal compounds have specific chronotropic properties.
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