These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Plasma thromboxane B2 concentration in patients with ventricular septal defect and pulmonary hypertension.
    Author: Fuse S, Tomita H, Chiba S.
    Journal: Jpn Circ J; 1998 Mar; 62(3):193-7. PubMed ID: 9583446.
    Abstract:
    Plasma thromboxane B2 (TXB2)-a stable metabolite of thromboxane A2 (TXA2)-conventional hemodynamic parameters, mean pulmonary input energy (input energy), and mean pulmonary output energy (output energy) were measured to assess platelet activation in 21 patients with pulmonary hypertension and a ventricular septal defect (VSD). The patients were divided into 2 groups: group A (normal range) and group B (high level). TXB2 levels were measured by radioimmunoassay. There was no relationship between plasma TXB2 concentrations and conventional hemodynamic parameters except the pulmonary-to-systemic pressure ratio. Output-to-input energy ratio was correlated logarithmically with the plasma TXB2 concentration. We concluded that patients with output/input energy ratio >0.15 had a high TXB2 concentration and activated platelets in pulmonary capillaries.
    [Abstract] [Full Text] [Related] [New Search]