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  • Title: Morphological variation in folded duplex DNA chains.
    Author: Yoshikawa Y.
    Journal: Nucleic Acids Symp Ser; 1997; (37):275-6. PubMed ID: 9586106.
    Abstract:
    I have monitored the packaging process of giant DNA chains with various condensing agents, such as polyamines, polyethylene glycol having pendant aminogroups and a lipospermine, under fluorescence microscopy. The detail morphological structure of the compacted DNA has been observed using electron microscopy. It has become clear that the difference in the folding process results in a large polymorphism of compacted DNA. I discuss the biological importance of controlling the compacted structure.
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