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  • Title: [Effect of the observance of diurnal fast of Ramadan on duodenal ulcer healing with lansoprazole. Results of a prospective controlled study].
    Author: Mehdi A, Ajmi S.
    Journal: Gastroenterol Clin Biol; 1997; 21(11):820-2. PubMed ID: 9587532.
    Abstract:
    OBJECTIVES: The aims of this study were: a) to determine whether patients with duodenal ulcer treated with a proton pump inhibitor may fast during the month of Ramadan, b) to evaluate the result of the treatment in this condition. METHODS: Fifty-seven patients with acute duodenal ulcer confirmed by endoscopy were included in the study. All the patients received 30 mg lansoprazole per day during 4 weeks. After randomization, patients of group I (n = 27) were dispensed from fasting, while those of group II (n = 30) fasted. Endoscopy was performed at the end of the month of the fast. RESULTS: The course of symptoms was not different in groups I and II. There were no ulcer complications. Healing rates at endoscopy were 88.8% and 90% in groups I and II, respectively. Fasting had no influence on the result of duodenal ulcer treatment by lansoprazole which was well tolerated. CONCLUSION: Patients with duodenal ulcer treated with lansoprazole may fast without running any risk.
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