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  • Title: Isolation and characterization of a new pyrano[4',3':6,7]naphtho[1,2-b]xanthene antibiotic FD-594.
    Author: Qiao YF, Okazaki T, Ando T, Mizoue K.
    Journal: J Antibiot (Tokyo); 1998 Mar; 51(3):282-7. PubMed ID: 9589063.
    Abstract:
    During our screening of microbial metabolites for effective drugs against tumor cell lines, we discovered a new pyrano[4',3':6,7]naphtho[1,2-b]xanthene derivative, FD-594 from the fermentation broth of Streptomyces sp. TA-0256. FD-594 shows moderate activity against tumor cell lines, comparative to that of adriamycin, as well as antibacterial activity against some Gram-positive bacteria.
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