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  • Title: [Significance of the expression of HLA-DR on keratinocytes in oral lichen planus lesions].
    Author: Guan Z, Li H.
    Journal: Zhonghua Kou Qiang Yi Xue Za Zhi; 1996 Jul; 31(4):238-40. PubMed ID: 9592279.
    Abstract:
    In this article, the expression of HLA-DR in keratinocytes in lesions of oral lichen planus (OLP) was investigated, using an immunohistochemical technique (PAP method). The results showed: HLA-DR positive keratinocytes were found in all groups of patients, the numbers and expressive degree of HLA-DR were related to types and duration of OLP, there were higher statistically significant differences between different groups and types of OLP (P < 0.01). The authors considered that the expression of HLA-DR in keratinocytes plays an important role in gathering T cells and forming inflammation in OLP lesions.
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