These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Antipneumococcal activity of grepafloxacin compared to that of other agents by time-kill methodology.
    Author: Pankuch GA, Jacobs MR, Appelbaum PC.
    Journal: Antimicrob Agents Chemother; 1998 May; 42(5):1263-5. PubMed ID: 9593163.
    Abstract:
    Time-kill studies compared the activities of grepafloxacin with those of ciprofloxacin, levofloxacin, sparfloxacin, amoxicillin-clavulanate, and clarithromycin against 12 pneumococcal strains. Grepafloxacin was bactericidal after 24 h against all strains at a concentration of < or = 0.5 microg/ml, while sparfloxacin, levofloxacin, and ciprofloxacin were bactericidal at concentrations of < or = 1.0, < or = 2.0, and < or = 8.0 microg/ml, respectively. Amoxicillin-clavulanate and clarithromycin were bactericidal at 2x the MIC after 24 h against 12 of 12 strains and against all 8 macrolide-susceptible strains, respectively.
    [Abstract] [Full Text] [Related] [New Search]