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  • Title: [Authors' experience with medical therapy of herpes genitalis in pregnancy].
    Author: Zarcone R, Fortuna G, Castagnolo A, Vicinanza G, Bellini P, Carfora E, Lizza R.
    Journal: Minerva Ginecol; 1998 Mar; 50(3):105-7. PubMed ID: 9595925.
    Abstract:
    BACKGROUND: Neonatal risk in herpes infections is very high: in the USA it is 1:2,000, in Japan 1:15,000 and in England 1:65,000. These differences seem to be due mostly to the different risk factors associated to the mother infection. The best strategy to cure herpes infection is to examine every patient during pregnancy and to identify the high risk ones. METHODS: In this study, 1,860 pregnant women have been submitted to a colposcopic and cytologic screening for the research of HSV. RESULTS: HSV was found in twenty (1.07%) women. Two groups have been made: the first with 14 HSV positive women at 3-6 months of pregnancy and second with 6 HSV positive women at eight months of pregnancy. Both groups were treated with acyclovir per os. The 14 women of the first group underwent vaginal delivery. The women of the second group underwent cesarean section. Only in 1 case a neonatal infection has been observed.
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