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  • Title: Guided tissue regeneration using a biodegradable barrier membrane for new attachment: a clinical, histologic, and histometric study in dogs.
    Author: O'Brien WD, Mishkin DJ, Engler WO, Miller MC, Neville BW.
    Journal: Int J Periodontics Restorative Dent; 1995 Oct; 15(5):446-61. PubMed ID: 9601245.
    Abstract:
    Although nonbiodegradable barrier membranes have proven partially successful in achieving regeneration of lost periodontium through the principles of guided tissue regeneration, their use requires a second surgical procedure for their removal. The results of a study, in which a biodegradable collagen membrane was used to treat dehiscence defects in dogs, are presented. The membrane was an effective barrier to the downgrowth of gingival epithelium during the early stages of healing and tended to increase the regeneration of new cementum and connective tissue attachment. It was also biocompatible and biodegradable.
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