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  • Title: [Thrombocyte lactate dehydrogenase isoenzymes in patients with ischemic stroke].
    Author: Khmara NF, Antonov IP, Trukhan AS.
    Journal: Zh Nevropatol Psikhiatr Im S S Korsakova; 1976; 76(7):1009-12. PubMed ID: 961281.
    Abstract:
    It was established that in the acute period of the ischemic stroke in the maiority of cases a change of isoenzyme structure of LDG thrombocytes was due to a decrease of LDG3 activity. In a number of patients the dominant change in the spectrum was determined by LDG and LDG4 fractions. The changes were of a stable character up to 10 weeks. LDG4 increase was characteristic of the isoenzymes spectrum in the patients with a severe development of the disease and in the patients in the remote period of the stroke. The obtained data can serve as a criterion for evaluating the adaptive changes in acute brain ischemia.
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