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  • Title: Predictors of duration of acute sinusitis episodes treated with antibiotics.
    Author: Lindbaek M, Hjortdahl P.
    Journal: Scand J Prim Health Care; 1998 Mar; 16(1):24-9. PubMed ID: 9612875.
    Abstract:
    OBJECTIVE: To evaluate which factors present at the onset of acute sinusitis predict the duration of illness among adult patients treated with antibiotics. DESIGN: Cohort study with a 30-day follow-up. SETTING: Norwegian general practice. SUBJECTS: Eighty-six adult patients with a clinical diagnosis of acute sinusitis confirmed by Computed Tomography. METHODS: Signs, symptoms and other variables present at the onset of treatment were dichotomized and analysed bivariately with duration of the sinusitis episode, using the log-rank test. Age, gender, and factors with p-values under 0.15 were modelled in a Cox regression analysis to assess independent predictors for illness duration. MAIN OUTCOME MEASURE: Duration of illness. RESULTS: Illness duration was significantly and positively associated with increasing age and with a higher clinical severity score at the onset of treatment. No other factors were independent predictors of illness duration. CONCLUSION: The age of the patient and the clinical severity of the sinusitis at the onset of treatment were independent predictors of illness duration in adult patients treated with antibiotics.
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