These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Serum levels of tumor necrosis factor alpha and production of this cytokine by polymorphonuclear cells in breast cancer patients.
    Author: Jabłońska E.
    Journal: Arch Immunol Ther Exp (Warsz); 1998; 46(2):93-6. PubMed ID: 9613706.
    Abstract:
    Unstimulated as well as zymosan and LPS-stimulated production of tumor necrosis factor alpha (TNF-alpha) by polymorphonuclear cells (PMNs) was investigated in breast cancer patients. Serum levels of TNF-alpha were also determined. Spontaneous TNF-alpha production was lower, comparable with that found in healthy persons. Zymosan and LPS-stimulated PMNs of cancer patients were found to produce significantly lower amounts of TNF-alpha, as compared with PMNs of healthy control. There was no significant differences in the serum levels of TNF-alpha between breast cancer patients and healthy persons. Because the peripheral blood cells contain more than 50% PMNs, the altered TNF-alpha production by PMNs may have a series of relevant implications during malignant process and seems to be one of the factors helpful in determining the cellular immunology potency of breast cancer patients.
    [Abstract] [Full Text] [Related] [New Search]