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  • Title: Vagal influence on serotonin concentration in enterochromaffin cells in the cat.
    Author: Ahlman H, Dahlström A, Kewenter J, Lundberg J.
    Journal: Acta Physiol Scand; 1976 Jul; 97(3):362-8. PubMed ID: 961448.
    Abstract:
    The intracellular concentrations of 5-HT in enterochromaffin cells of the jejunum, midgut and ileum of the cat have been estimated by a cytofluorimetric method before and after various periods of peripheral vagal nerve stimulation. The fluorescence intensities in randomized cell samples were measured photometrically after a standard illumination time before and after nerve stimulation. A significant decrease in 5-HT concentration in the enterochromaffin cells all through the small intestine could be demonstrated, which is in support of the hypothesis of a neurogenic release of 5-HT from enterochromaffin cells, possibly caused by vagal adrenergic fibres.
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