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  • Title: [Laugier-Hunziker syndrome. A clinical and anatomopathologic study. Presentation of 13 cases].
    Author: Seoane Lestón JM, Vázquez García J, Cazenave Jiménez AM, de la Cruz Mera A, Aguado Santos A.
    Journal: Rev Stomatol Chir Maxillofac; 1998 Apr; 99(1):44-8. PubMed ID: 9615354.
    Abstract:
    We report the clinico-pathologic characteristics of 13 cases of Laugier-Hunziker disease, consisting of the presence of oral melanotic macules associated or not to longitudinal nail pigmentation. The presence of regular acanthosis, basal pigmentation without increase in the number of melanocytes and the presence of melanophages in subepidermal connective tissue have been the most constant histopathological characteristics. The term "essential cutaneo-mucous hyperpigmentation" as synonym of Laugier-Hunziker disease is proposed.
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