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  • Title: Isolation of (copper, zinc)-thioneins from the livers of copper-injected rats.
    Author: Bremner I, Young BW.
    Journal: Biochem J; 1976 Aug 01; 157(2):517-20. PubMed ID: 962883.
    Abstract:
    The mixed copper- and zinc-binding proteins, with mol.wt. of approx. 12000, induced in rat liver after injection of copper were isolated and characterized as metallothioneins. Three separate forms were obtained, with 7-11% total metal in the protein, equivalent to 2.6-1.6 cysteine residues/metal atom.
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