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Title: Sugar cell responses to lactose and sucrose in labellar and tarsal taste hairs of Musca domestica. Author: Schnuch M, Seebauer H. Journal: J Comp Physiol A; 1998 Jun; 182(6):767-75. PubMed ID: 9631555. Abstract: Receptor cell responses in the largest labellar (LL) and tarsal (D) taste hairs of the housefly Musca domestica were investigated electrophysiologically using the tip-recording technique. In LL hairs, test series with lactose in concentrations of 12.5-400 mmol.l-1 yielded a threshold concentration around 12 mmol.l-1 and a calculated concentration eliciting half-maximal response of around 40 mmol.l-1, the maximal response varying between 18 and 30 impulses/300 ms. D hairs are more sensitive towards lactose, indicated by a slightly lower threshold and a by 60% higher response to 400 mmol.l-1 lactose. The high variation in the relative stimulating effectiveness of lactose and sucrose and experiments with sugar mixtures imply that these sugars bind to different receptor sites without noticeable cross affinity. A comparison of the concentration response characteristics for sucrose and lactose in LL and D hairs suggests that sucrose can combine with more than one site type, expressed in different proportions in both hair types. Results obtained with p-nitrophenyl-beta-galactoside as stimulus indicate that a beta-galactoside link is not sufficient for a substance to interact specifically with the lactose binding site. The exceptional lactose sensitivity of the sugar cell in M. domestica is discussed in the context of food acquirement and digestion.[Abstract] [Full Text] [Related] [New Search]