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  • Title: Electron microscopic examination of Aedes albopictus clone C6/36 cells infected with dengue virus 2 at elevated incubation temperature.
    Author: Pandey B, Ichinose A, Igarashi A.
    Journal: Acta Virol; 1998 Feb; 42(1):35-9. PubMed ID: 9645241.
    Abstract:
    Morphological changes such as loss of cytoplasm, membrane destruction and vacuolar swelling in Aedes albopictus clone C6/36 cells infected with dengue virus 2 (DV-2) New Guinea B strain and incubated at 28 degrees C and 37 degrees C, were observed under electron microscope. Both infected and uninfected cells showed significant damage at 37 degrees C in contrast to normal appearance at 28 degrees C. A higher number of virus particles were observed in the cytoplasm at 37 degrees C than at 28 degrees C.
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