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  • Title: Rifabutin-associated uveitis in an immunosuppressed pediatric patient without acquired immunodeficiency syndrome.
    Author: Jewelewicz DA, Schiff WM, Brown S, Barile GR.
    Journal: Am J Ophthalmol; 1998 Jun; 125(6):872-3. PubMed ID: 9645728.
    Abstract:
    PURPOSE: To describe a case of bilateral, symptomatic rifabutin-associated uveitis with hypopyon and vitreal opacities in an immunosuppressed pediatric patient without acquired immunodeficiency syndrome (AIDS). METHOD: Case report. An 8-year-old boy presented with bilateral uveitis 24 months after a bilateral lung transplant. RESULTS: Our patient, whose medications included rifabutin, clarithromycin, and immunosuppressive agents, responded to discontinuation of the rifabutin and initiation of intensive topical corticosteroid therapy with complete resolution of the uveitis. CONCLUSION: Rifabutin-associated uveitis may occur in a non-AIDS pediatric patient.
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