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  • Title: Treatment of phenothiazine-induced dyskinesia.
    Author: Goldman D.
    Journal: Psychopharmacology (Berl); 1976 Jun 23; 47(3):271-2. PubMed ID: 9653.
    Abstract:
    Previous experience indicated the possibility that a serotonin antagonist substance, was effective in relieving dyskinesia as a reaction to phenothiazine antipsychotic drugs. Since the substances used in the original observations did not become available on the United States market, a compound known to be a serotonin antagonist, cyproheptadine, which was readily available and safe, was used to treat three patients who had phenothiazine-induced dyskinesia. In these patients, cyproheptadine was definitely effective in relieving the dyskinesia over an extended period of time. Further controlled studies are required to confirm this report.
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