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  • Title: [Indocyanine green video angiographic findings of frosted branch angitis in a child].
    Author: Tanikawa H, Akimoto S, Honda M, Kobayashi Y, Nakamura O.
    Journal: Nippon Ganka Gakkai Zasshi; 1998 Jun; 102(6):399-404. PubMed ID: 9656692.
    Abstract:
    A 10-year-old boy presented with typical fundus findings of frosted branch angitis in both eyes. Fluorescein angiography showed late-phase hyperfluorescence in some active areas of vascular lesions. Indo-cyanine green (ICG) angiography showed similar but less extensive hyperfluorescence along the frosted vessels and in the disc. ICG angiography also showed filling delay in the choriocapillaris. These findings suggest that frosted branch angitis is a manifestation of inflammation in the retina and the choroid. Laboratory studies showed increase in the toxoplasma titer at 1:10,240 and in the serum levels of alpha 1 and alpha 2 globulin. Frosted branch angitis in this case seemed to be the consequence of local allergic reaction, or immune complex deposition, presumably due to toxoplasma infections.
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