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  • Title: Solitary enchondroma with clonal chromosomal abnormalities.
    Author: Gunawan B, Weber M, Bergmann F, Wildberger J, Füzesi L.
    Journal: Cancer Genet Cytogenet; 1998 Jul 15; 104(2):161-4. PubMed ID: 9666812.
    Abstract:
    We report a case of a solitary enchondroma located in the head of the left fibula in a 50-year-old patient and present the findings of histopathologic investigation and cytogenetic analysis. The tumor revealed simple karyotypic abnormalities with t(8;17)(q23;p13) and loss of chromosomes 9, 19, and 22 as clonal chromosomal changes. Only a few enchondromas with chromosome aberrations have been published previously; nevertheless, it appears that benign and malignant cartilaginous tumors may have similar chromosomal abnormalities.
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