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Pubmed for Handhelds

PUBMED FOR HANDHELDS

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  • Title: Latex: a cause of allergic contact eczema in users of natural rubber gloves.
    Author: Wilkinson SM, Burd R.
    Journal: J Am Acad Dermatol; 1998 Jul; 39(1):36-42. PubMed ID: 9674395.
    Abstract:
    BACKGROUND: Latex is a common cause of contact urticaria in glove users. We recently found that 1.2% of patients attending a contact dermatitis investigation unit had delayed type hypersensitivity to latex as a cause of eczema. OBJECTIVE: We reassessed the relevant contact allergens in users of natural rubber gloves with hand dermatitis. Particular emphasis was placed on allergens not included in the standard patch test series. METHODS: Consecutive natural rubber glove users with hand dermatitis were investigated for the presence of contact dermatitis and urticaria. RESULTS: One hundred seventeen consecutive patients were tested. The American standard series missed 34% and the European 40% of patients with positive patch test reactions to rubber related chemicals. Six percent of patients (20% of those with a positive reaction) demonstrated delayed type hypersensitivity to latex, often in the absence of other relevant contact allergens and contact urticaria to latex. CONCLUSION: Latex is a relatively common cause of allergic contact eczema in the absence of contact urticaria. Latex should be included in a rubber series for screening patients with hand dermatitis who are glove users.
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