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  • Title: [Detection of HIV antibodies in pooled sera].
    Author: López G, Silva C, Benítez J.
    Journal: Rev Cubana Med Trop; 1997; 49(1):32-7. PubMed ID: 9685958.
    Abstract:
    The use of sera mixtures for the detection of HIV antibodies was studied in a population of low prevalence (0.006%), using the diagnosis systems of national production: Recombinant HIV UMELISA and RECHIV 1 + 2. The systems were evaluated with individual samples and mixtures of 5 and 10 sera from healthy blood donors and from HIV-1 and/or HIV-2 positive and undetermined persons. It was observed that the utilization of mixtures of 10 sera is not feasible; however, the use of mixtures of 5 affects neither the specificity nor the sensitivity of the systems studied.
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