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  • Title: [Use of doxazosin (Cardura-Pfizer), alpha 1-adrenoreceptor antagonist, in treatment of hypertension in patients with diabetes].
    Author: Grzeszczak W.
    Journal: Wiad Lek; 1998; 51 Suppl 2():5-10. PubMed ID: 9686527.
    Abstract:
    Doxazosin (Cardura-Pfizer) is a alpha 1-adrenoreceptor antagonist. This drug significantly decreases the blood pressure in subjects with hypertension. Despite decreasing blood pressure, doxazosin has a beneficial effect on many disorders observed in subjects with diabetes mellitus. Doxazosin 1) improves the regulation of lipids disturbances, 2) improves tissue sensitivity to insulin, 3) decreases the frequency of sexual disorders. In this situation Doxazosin is a good choice in the treatment of hypertension in diabetic subjects, in subjects with hypertension and hypercholesterolemia, with left ventricular hypertrophy, in old male subjects with hypertension and benign prostatic hypertrophy.
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