These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Successful use of tissue plasminogen activator (t-PA) in catheter-related intracardiac thrombi of two premature infants.
    Author: Giuffrè B, Compagnoni G, Farina C, Mosca F.
    Journal: Acta Paediatr; 1998 Jun; 87(6):695-8. PubMed ID: 9686666.
    Abstract:
    We describe the cases of two premature infants carrying a central venous line who developed on the fourth day of life a catheter related intracardiac thrombus. Although they were clinically asymptomatic we opted for thrombolytic treatment considering the potential risks of this situation. Treatment with recombinant tissue plasminogen activator (rt-PA) was performed for one day in the first case and for three days in the second one, in association with fresh frozen plasma. Thrombus dissolution occurred in both patients and no adverse effects were noted. In our experience tissue plasminogen activator was a therapy acceptably safe and effective inducing clot lysis in very low birthweight neonates into critical situations.
    [Abstract] [Full Text] [Related] [New Search]