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  • Title: Cytokines in the modulation of eosinophilia.
    Author: Faccioli LH, Vargaftig BB, Medeiros AI, Malheiros A.
    Journal: Mem Inst Oswaldo Cruz; 1997; 92 Suppl 2():109-14. PubMed ID: 9698922.
    Abstract:
    In this review we discuss our recently results showing interleukin 5 (IL-5) involvement in eosinophil migration and in the maintenance of eosinophilia in blood, bone marrow, lung and peritoneal cavity, in a visceral larva migrans syndrome model using guinea-pigs infected with Toxocara canis. We also describe the sequential release of TNF-alpha and IL-8 during the course of infection. Finally we propose a biological role for IL-5, at least in our model, as a modulator of IL-8 release and secretion.
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