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  • Title: CNS effects of a series of 1,2,4-triazolyl heterocarboxylic derivatives.
    Author: Darias V, Abdala S, Martin-Herrera D, Tello ML, Vega S.
    Journal: Pharmazie; 1998 Jul; 53(7):477-81. PubMed ID: 9699225.
    Abstract:
    A series of 1,2,4-triazolyl heterocarboxylic derivatives were tested for acute toxicity and CNS effects in mice. Several of these compounds demonstrated clear psychostimulant effects. Other components of the series, however, showed a definite central depressant activity. Some of the screened derivatives showed interesting anxiolytic properties.
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